Our Portfolio

We take an active role in our portfolio companies, contributing expertise in drug discovery, development and operations, to help them deliver maximum patient value.

Direct Investments

Switch Therapeutics

Switch Therapeutics is a San Francisco based biotech developing conditionally activated siRNA technology for central nervous system diseases.

Code Bio

Code Bio is developing transformational, non-viral, genetic medicines to treat and potentially cure serious and life-threatening diseases

SpliceBio

SpliceBio is a biotechnology company exploiting protein splicing to develop the next generation of gene therapies

Neurona Therapeutics

Neurona is a cell therapy company focused on the development of breakthrough treatments for neurological disorders.

Walden Biosciences, Inc

Walden Biosciences, Inc., a biotechnology company focused on transforming the treatment of kidney disease.

Rinri Therapeutics

Rinri Therapeutics is a biotechnology company developing advanced stem cell-based therapeutics to treat hearing loss.

ExeVir Bio

ExeVir Bio is an VHH antiviral platform company focused on rapid control with a lead compound for COVID-19.

ViaNautis

ViaNautis is developing a nanovesicle platform designed to deliver genetic therapeutic payloads to the specific site of action with unparalleled precision.

Iris Medicine

Iris Medicine is developing a unique RNA therapeutics platform that enables universal allele selectivity in treating genetic diseases.

Seamless Therapeutics

Seamless is developing a unique approach to gene editing using programmable recombinases to address genetic disease.

Cenos Therapeutics

Cenos is pioneering a blood-brain barrier shuttle platform to address neurological diseases with high unmet needs.

Selected Invested Funds

Arix Bioscience

arixbioscience.com Arix Bioscience supports medical innovation at all stages of development and has access to breakthrough academic science.

Pappas Capital

Pappas is dedicated to furthering life science discoveries and delivering groundbreaking solutions to market.

Qiming

Qiming drives innovation and growth of business enterprises and promotes overall industry advancement and social development.

Waterline Ventures

Waterline invests in early growth technology and service-enabled technology companies in the healthcare space.

AVP

Exited

Syndesi Therapeutics

Syndesi Therapeutics is developing novel modulators of the synaptic vesicle protein SV2A to address disorders of cognition. Acquired by AbbVie.

Ally Therapeutics

Ally Therapeutics is a gene therapy company spun out of Harvard.

StrideBio

StrideBio, Inc. is a gene therapy company focused on creating and developing novel adeno-associated viral (AAV) vector technologies.

Locana

Locana, Inc. is an RNA-targeting gene therapy company with a platform technology to address a wide spectrum of human genetic diseases.

EsoBiotec

EsoBiotec is a biotechnology company developing an in vivo engineering platform to produce cancer fighting cells inside the patient’s body. Acquired by AstraZeneca.

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